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Clinical Manual of Psychopharmacology in the Medically Ill

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The new edition of Clinical Manual of Psychopharmacology in the Medically Ill continues the legacy and builds on the success of the first edition by offering a thoroughly up-to-date, comprehensive, and practical guide to the prescription of psychotropic medications in patients with medical illness. The book addresses the prevalence of psychiatric illness in patients with serious medical illness, the complications that may arise, and the implications for psychopharmacological treatment. There is increasing recognition that patients with medical and psychiatric comorbidity have more functional impairment, disability days, emergency department use, rehospitalization, and other medical care costs than do those without such comorbidity. As a result, health care systems have been incentivized to develop new and innovative models of population-based care that integrate medical and psychiatric care in an effort to increase quality and prevention while decreasing use of expensive services such as emergency department visits and hospitalizations. The book is a valuable guide for clinicians across a range of specialties operating in this new, more demanding health care environment.

The manual addresses critically important topics through the use of a variety of user-friendly features: • Psychiatric drugs that have become available since the first edition, as well as all recent relevant randomized controlled trials, systematic reviews, and meta-analyses, are covered thoroughly.• Each chapter addresses key differential diagnostic considerations and adverse neuropsychiatric side effects of disease-specific medications.• Disease-specific pharmacokinetic principles in drug prescribing, including interactions between psychotropic drugs and disease-specific drugs, are also addressed.• Key summary points pertaining to psychotropic prescribing in the specific medical disease(s) or specialty area covered are included at the end of each chapter, and a multitude of useful tables summarizing the most important information are provided as well.• Chapters are heavily referenced with source information should readers wish to expand their knowledge in a specific area.

The chapter authors were selected for their expertise in each area, then the text was edited for consistency, clarity, and maximum utility. Clinical Manual of Psychopharmacology in the Medically Ill is a rigorous and illuminating guide to this vital topic, and clinicians from a variety of specialties will find it indispensable.

ISBN-13: 9781615375134

Media Type: Paperback

Publisher: American Psychiatric Association Publishing

Publication Date: 10-18-2023

Pages: 896

Product Dimensions: 8.20h x 5.50w x 1.30d

Age Range: 18 Years

James L. Levenson, M.D., is Professor of Psychiatry, Medicine, and Surgery and Vice-Chair for Clinical Services in the Department of Psychiatry at Virginia Commonwealth University School of Medicine in Richmond, Virginia.Stephen J. Ferrando, M.D., is Professor of Psychiatry and Chairman of the Department of Psychiatry at Westchester Medical Center Health Network of New York Medical College in Valhalla, New York.

What People are Saying About This

Michael Sharpe MA MDEmeritus Professor of Psychological Medicine University of OxfordPast President

The use of psychoactive drugs in the medically ill is an important, complex, and often perplexing field. This reference book is correspondingly not only important but also superb in providing much needed guidance by describing both general principles and summarizing the relevant literature. This useful manual starts with basic pharmacology and routes of administration, then walks the reader though the effects, adverse-effects and interactions of these drugs in patients with disease in each bodily system. The combination of clinical wisdom and comprehensive reviews of the literature make this book indispensable not only to consultation-liaison psychiatrists but also to any physician interested in the effects on brain and behaviour of the drugs they routinely use.

Alan F. Schatzberg

As patients live longer medical comorbidity has become exceedingly common with various psychiatric disorders, including major depression and bipolar disorder. Indeed, some of our primary treatments for these disorders may actually lead to this comorbidity because of biological consequences of specific pharmacology agents. Thus, today we can no longer easily separate medical and psychiatric disorders in our approaches to specific patients. Indeed, a wider knowledge of the interface is needed for everyday practice. In this vein we need to consider medical status when prescribing psychotropic agents. The Second Edition of this Manual helps all of us to practice better and is a must read. Its first edition was an enormous step forward for the field and this Second Edition will only bring us further up to date on how best to prescribe psychotropic drugs in treating co-morbid patients.

James A. Bourgeois

(This manual) is a timely, highly pragmatic, thorough, and essential volume for psychosomatic medicine (PSM). Thoughtfully dedicated to their late colleague and collaborator James Owen (who was an author on several chapters), the book takes a clinically and scientifically grounded approach to the myriad challenges of the management of co-morbid psychiatric and systemic illness. This volume should be available to every PSM psychiatry service and should also be of interest to the general psychiatrist who is expected to function in a PSM role on occasion.

Michael Sharpe

The use of psychoactive drugs in the medically ill is an important, complex, and often perplexing field. This reference book is correspondingly not only important but also superb in providing much needed guidance by describing both general principles and summarizing the relevant literature. This useful manual starts with basic pharmacology and routes of administration, then walks the reader through the effects, adverse-effects and interactions of these drugs in patients with disease in each bodily system. The combination of clinical wisdom and comprehensive reviews of the literature make this book indispensable not only to consultation-liaison psychiatrists but also to any physician interested in the effects on brain and behaviour of the drugs they routinely use.

Philip R. Muskin

The first edition of this book was an instant "must have" for all psychiatrists, whether they treat patients with comorbid medical conditions or not. The second edition of the Manual is even better, updated and another "must have" book for all psychiatrists. The evidence supporting the use for or against a medication in a particular medical illness is reviewed succinctly. I particularly liked the Key Points at the end of each chapter as they provided a summary of the take home messages. Congratulations to the authors and editors for producing such a valuable textbook.

Prof. Massimo Biondi

Psychiatric disorders and medical illness are often comorbid. Psychopharmacological treatment thus poses several efficacy and safety challenges. This manual covers the main—if not all of—the needs that psychiatrists and medical specialists have in the psychopharmacological treatment of medical patients. It is extraordinary well documented, updated, and precise. The manual is both a very useful resource for the clinician and a clear educational tool for students. This second, enriched new edition promises an even better success than the previous one.

Anthony J. Rothschild

As the population ages, it is increasingly common to be prescribing psychotropic medications to patients who are also being treated with other medications for co-occurring medical conditions. Thus, it is important for the practitioner to understand the interface of psychiatric and medical diseases and the effects of psychotropic and nonpsychotropic medications on each other. Consequently, the Clinical Manual of Psychopharmacology in the Medically Ill is a must-have for every psychiatrist's and primary care provider's bookshelf! Now in its Third Edition, the book is conveniently organized by medical illness with comprehensive discussions regarding pharmacokinetics, pharmacodynamics, principles of drug-drug interactions, and severe drug reactions. At the end of each chapter are "Key Points" that succinctly summarize the important points to remember. The book is a useful tool for the busy practitioner because it synthesizes a large amount of information in an easy-to-read manual with clear explanations.

Table of Contents

ContributorsDedicationAcknowledgmentsIntroductionPart I: General PrinciplesChapter 1. Pharmacokinetics, Pharmacodynamics, and Principles of Drug-Drug InteractionsChapter 2. Severe Drug ReactionsChapter 3. Alternative Routes of Drug AdministrationPart II: Psychopharmacology in Organ System Disorders and Specialty AreasChapter 4. Gastrointestinal Disorders Chapter 5. Renal and Urological DisordersChapter 6. Cardiovascular DisordersChapter 7. Respiratory DisordersChapter 8. OncologyChapter 9. Central Nervous System DisordersChapter 10. Endocrine and Metabolic DisordersChapter 11. Obstetrics and GynecologyChapter 12. Infectious DiseasesChapter 13. Dermatological DisordersChapter 14. Rheumatological DisordersChapter 15. Surgery and Critical CareChapter 16. Organ TransplantationChapter 17. Pain ManagementChapter 18. Substance Use DisordersIndex